The NR2F2 gene encodes the transcription factor COUP-TFII, which is upregulated in embryonic mesoderm.Heterozygous variants in NR2F2 cause a spectrum of congenital anomalies including cardiac and gonadal peavey kb1 phenotypes.We generated heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2-knockout induced pluripotent stem cell (iPSC) l
The spastic hemiplegia is a motion defect of a part of the body, either on the right or left side.The disability is not always uniform.The kinetic means have an important contribution to the recovery of the children spastic hemiplegia, being opi meet my decorator included in the treatment plan of the followed subjects, these means have the purpose
Intranasal delivery provides a practical, noninvasive method of bypassing the blood-brain barrier (BBB) in order to deliver therapeutic agents to the brain.This method allows drugs that do not cross the BBB to be delivered to the central nervous system in a few minutes.With this technology, it will be possible to eliminate systemic administration a